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Scientific Research

Stay apprised of findings from across the field with summaries of research published in SfN journals, and learn about rigor, responsible conduct of research, and other topics important to the scientific community.
Members of the Amazon research team and Valeria Muoio.
Scientific Research
Neuroscience and Mental Health in the Amazon
Cultural Influences on the Way to Do and Interpret Our Science
Scientific Research
Cultural Influences on the Way to Do and Interpret Our Science
July 17, 2024 1:00 PM - 2:00 PM EDT
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  • Scientific Image
    Pose Estimation for Lab Animals Using Deep Learning
  • Learning to Predict Fly Behavior
  • Scientific Image
    Mining Morphological Features of Neurons with PRISM
  • 2. This image shows a cross section of a day 28 human forebrain organoid, showing FOXG1-expressing neural precursors (Red), surrounding a ventricle-like structure outlined by N-Cadherin staining (Green). DAPI staining is blue.
    Fos Activation
  • This image shows superposed axonal reconstructions of the four interneuron populations found in mouse neocortical layer 1: canopy cells (orange), neurogliaform cells (green), a7 cells (purple), and VIP cells (blue).
    Calcium Imaging
  • This 3D reconstruction of immunofluorescence staining shows microglial cell activation (Green, Iba1 marker) 30 days after an embolic stroke, with infiltration of the hippocampal formation and reduced density of synaptic connections (Red, SV-2) among neurons (Magenta, NeuN). This invasion can be inhibited by early targeting of the complement components of innate immunity.
    Chemogenetics
  • This image shows GFAP-Cre activity (tdTomato/red) in a choroid plexus (marked by β-catenin/green) of a lateral ventricle of mouse brain at postnatal day 7.
    Neuroimaging
  • This image shows ventral striatal neurons from a rodent brain. The cell bodies are stained in blue using a fluorescent NISSL stain (NeuroTrace). A light sensitive virus for optogenetics was transducted into neurons shown in yellow. Neurons in this area are involved in scaling fear to the degree of threat and in rapid discrimination of uncertain threat and safety.
    Tutorial 2: Classifiers and Regularizers
  • This mirrored image shows a CA1 neuron before (left side) and after (right side) activation of excitotoxicity by metabotropic NMDA receptors and pannexin-1, a postsynaptic ion and metabolite channel. Metabotropic NMDAR signaling regulates pannexin-1 through Src kinase. This pathway suppresses facilitated release of presynaptic glutamate during synaptic activity by regulating tissue levels of the TRPV1 agonist anandamide.
    Machine Learning II: Outro Lecture
  • 2. This image shows a cross section of a day 28 human forebrain organoid, showing FOXG1-expressing neural precursors (Red), surrounding a ventricle-like structure outlined by N-Cadherin staining (Green). DAPI staining is blue.
    Machine Learning I: Intro Lecture
  • This image shows a retinal section from a mouse in which a subset of amacrine cells was labeled with an antibody against the transcription factor Meis 2 (green), which was identified in a single-cell RNA sequencing expression screen that characterized >60 amacrine cell types. The section was also stained to mark two classes of inhibitory neurons, GABAergic (magenta) and glycinergic (cyan).
    Tutorial 1: Generalized Linear Models (GLMs)
  • Image of Karl herrup
    Fallacies in Neuroscience
    February 22, 2022 12:00 PM - 1:00 PM ET
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